Iran's Supreme Leader Ayatollah Ali Khamenei said on November 3 that cooperation with the United States could only be considered if Washington completely withdraws support for Israel, removes military bases from the region and ceases interference, but "not now, and not in the near future", Leader website reported on November 3.

Speaking to students ahead of the anniversary of the 1979 US Embassy takeover, Khamenei said the dispute between Iran and the United States stems from a fundamental conflict of interests between two opposing currents, not tactical differences.

He said the severed ties between Iran and the United States are rooted in an ideological clash, asserting that America's "hegemonic nature" demands submission, which he described as unacceptable for Iran.

"All American presidents have wanted this, though they rarely say it aloud," Khamenei said. "But the current president [Donald Trump] has revealed America's true intentions."

Khamenei traced US-Iran tensions to the August 19, 1953 coup that overthrew Prime Minister Mohammad Mossadegh's government, which had nationalised Iran's oil industry, something which he and the Islamic Republic have always been shy to connect to the later 1979 revolution.

He said the US cooperated with Britain in the coup and returned the Shah to power, beginning "25 years of dictatorship" backed by Washington and Western countries.

He described the November 4, 1979 seizure of the US Embassy by Iranian students as a day of "pride and victory" that revealed America's true identity and the real nature of the Islamic Revolution.

Khamenei said students initially planned a two- to three-day occupation to express Iranian anger, but discovered documents showing the embassy served as a conspiracy centre against the revolution.

Khamenei rejected claims that the "Death to America" slogan causes US hostility towards Iran, calling this interpretation a reversal of history. He said the fundamental issue is incompatibility between America's hegemonic nature and the Islamic Republic's independence-seeking character.

He said resolving many problems and securing the country requires strength in management, science, military capability and motivation, calling on the government to work forcefully in relevant sectors.

Khamenei's comments may be interpreted as a green light for talks between the US and Iran, which the country's foreign minister, Abbas Aragchi, said could potentially restart if the US were to meet certain conditions, including no further attacks against the country's infrastructure.