Protests have erupted across Pakistan in response to the death of Iran’s supreme leader Ali Khamenei in an air strike on Tehran on February 28, local media Dawn reports. At least 10 people have been reported dead after clashes near the heavily protected US consulate in the port city of Karachi, but that number is expected to rise..

Hospital officials in the southern city confirmed that 10 fatalities were recorded while another 31 were admitted with varying degrees of injury. All are believed to have been the victims of gunfire, Dawn adds. At least one video circulating on social media appears to show a guard at the US consulate firing a weapon but it is still unclear if the gunshots were the result of local police or consulate guards firing on protestors.

Sindh provincial government officials for now, however, are putting the death toll at six, with a comment issued that several others were injured.

Social media images appear to show law enforcement officers firing tear gas and using batons in an attempt to disperse crowds just inside the consulate’s security perimeter.

Elsewhere in Pakistan there have been further demonstrations. Known protests have taken place in Lahore, the Pakistani capital Islamabad and areas of the mountainous Gilgit-Baltistan region, reports say. The protests are believed to be directed at Washington and Israel, and are a direct response to the strike that killed Iran’s supreme leader.

In a security advisory, the US embassy in Islamabad said on social media “We are monitoring reports of ongoing demonstrations at the US Consulates General in Karachi and Lahore, as well as calls for additional demonstrations at US Embassy Islamabad and Consulate General Peshawar.”

The embassy also urged US citizens to avoid large crowds.

In Lahore, several hundred activists linked to the Majlis Wahdat-i-Muslimeen, a Shiite Muslim political and religious party, are reported to have assembled outside the US consulate late in the morning, hours ahead of a rally scheduled for the afternoon.

The protesters, many carrying pictures of the dead Khamenei, chanted anti-US as police cordoned off surrounding streets to prevent additional groups from marching on the diplomatic enclave.

Further north, Dawn reports authorities have imposed a curfew in Skardu after demonstrators set fire to premises used by the United Nations Military Observer Group in India and Pakistan (UNMOGIP). Local reports have also added that a school, a police facility and a rural support group were burnt.